While the abstract referenced below is short, it makes mention of a number of key points, each suggesting that an inflammatory process may be at work in fibromyalgia: The cerebro-spinal fluid (CFS) of those with fibromyalgia has been shown to contain higher than normal levels of substance P and corticotropin releasing hormone (CRH). The blood…
One of the more unusual symptoms of fibromyalgia is a skin rash. It’s unusual in terms of frequency (perhaps 10% of those with fibromyalgia report a skin rash?) But it’s more unusual in that it’s hard to explain why fibromyalgia should cause a skin rash. At least it’s hard to explain if you accept the…
Some fibromyalgia patients seem to respond relatively well to non-steroidal anti-inflammatory drugs (NSAIDs.)
Some fibromyalgia patients (about 30% in the study below) have evidence of neurogenic inflammation on skin biopsy. This might explain, at least in part, why some patients respond better than others to NSAIDs.
