Nitric oxide synthase inhibitors prevent CGRP mediated dilation of blood vessels in a model of migraine.
Nitric oxide synthase inhibitors can antagonize neurogenic and calcitonin gene-related peptide induced dilation of dural meningeal vessels.
Summary of the abstract
CGRP antagonists can block both neurogenic and CGRP-induced dural vessel dilation.
Nitric oxide synthase (NOS) inhibitors are effective in the treatment of acute migraine.