Unlike most other auto-immune disease, those with Sjogren’s do not experience relapses and remissions. That is, patients do not have periods of relatively high disease activity with intervening times of no or little active disease.
Why, among all auto-immune conditions, is Sjogren’s characterized by a steadily progressive course?
One form of multiple sclerosis, primary progressive multiple sclerosis, has from its onset a steadily progressive course. And relapsing-remitting multiple sclerosis eventually progresses to a steadily progressive phase in many.
Do Sjogren’s and the progressive forms of multiple sclerosis share some common characteristic?