Irritable bowel syndrome is associated with an increase in circulating pro-inflammatory cytokines, including IL-8.
Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: role of muscarinic receptors.
Summary of the Abstract
Irritable bowel syndrome has been linked to immune activation. The pro-inflammatory cytokine profile in irritable bowel syndrome is investigated.
Both IL-6 and IL-8 are found to be elevated in those with irritable bowel syndrome.
It is concluded that irritable bowel syndrome is characterized by a pro-inflammatory cytokine profile.