Ginger extracts can be used to improve a diabetic situation
Impact of the 5-HT(3) receptor channel system for insulin secretion and interaction of ginger extracts
Summary of the abstract
The relevance of serotonin and in particular that of 5-HT(3) receptors is unequivocal with respect to emetic/antiemetic (anti-nausea, anti-vomiting) effects, but it is controversial with respect to antidiabetic effects (regarding improved control over blood sugar levels.)
The effects of tropisetron (5-HT(3) receptor antagonist) and various ginger (Zingiber officinale) extracts (known to interact with the 5-HT(3) receptor channel system) were investigated. The in vitro data with respect to ginger are corroborated by in vivo data on glucose-loaded rats showing that blood glucose (Glucoquant((R))) is decreased by ~35% and plasma insulin (RIA) is increased by ~10%.
It may be concluded that serotonin and in particular the 5-HT(3) receptor channel system are involved in modulating insulin release and that tropisetron and various ginger extracts can be used to improve a diabetic situation.
Ginger appears to improve control of blood sugar in type 2 diabetics
Test tube experiments (“in vitro” means “in glass”) demonstrated that ginger components caused the release of additional insulin when that insulin release had been artificially blocked. In vivo (in life) experiments were then carried out on rats. These rat experiments confirmed the effect of ginger in a living mammal (though not a human.) Glucose levels decreased by 35% and insulin levels increased by 10%.