Type 2 diabetes has been found to increase the risk of developing Alzheimer’s disease.

Both Alzheimer’s and type 2 diabetes are associated with excess inflammation. NF-kB may be the critical link between these two conditions.

The publication:

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J Alzheimers Dis. 2009 Apr;16(4):809-21.

Inflammation and NF-kappaB in Alzheimer’s disease and diabetes.

Granic I, Dolga AM, Nijholt IM, van Dijk G, Eisel UL.

Department of Molecular Neurobiology, University of Groningen, Haren, The Netherlands.

Summary of the abstract

Inflammatory processes are a hallmark of many chronic diseases including Alzheimer’s disease and diabetes mellitus.

Fairly recent statistical evidence indicating that type 2 diabetes increases the risk of developing Alzheimer’s disease has led to investigations of the potential common processes that could explain this relation.

This publication reviews how NF-kB might be involved in both diabetes mellitus and Alzheimer’s disease.

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