Efficacy of curcumin demonstrated in rheumatoid arthritis, inflammatory eye diseases, inflammatory bowel disease, chronic pancreatitis, psoriasis, hyperlipidemia, and cancers
Patients taking up to 8 grams of pure curcumin daily for 4 months reported no significant side effects.
The publication:
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Adv Exp Med Biol. 2007;595:471-80.
Clinical studies with curcumin
Hsu CH, Cheng AL.
Summary of the abstract
Curcumin has long been expected to be a therapeutic or preventive agent for several major human diseases because of its antioxidative, anti-inflammatory, and anticancerous effects.
In phase I clinical studies, curcumin with doses up to 3600-8000 mg daily for 4 months did not result in discernible toxicities except mild nausea and diarrhea.
The pharmacokinetic studies of curcumin indicated in general a low bioavailability of curcumin.
The effect of curcumin was studied in patients with rheumatoid arthritis, inflammatory eye diseases, inflammatory bowel disease, chronic pancreatitis, psoriasis, hyperlipidemia, and cancers.
Although the preliminary results did support the efficacy of curcumin in these diseases, the data to date are all preliminary and not conclusive. It is imperative that well-designed clinical trials, supported by better formulations of curcumin or novel routes of administration, be conducted in the near future.
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Comments:
The only ‘problem’ with curcumin is solved by a novel route of administration
The only ‘problem’ with curcumin seems to be its low level of bio-availability. That is, not enough curcumin gets into the blood, and to the cells where it can exert its beneficial effects.
Banjo delivers turmeric (and curcumin, its major active ingredient) trans-mucosaly. That is, the active ingredients are absorbed through the mucous membranes of the mouth. This is believed to substantially increase the bio-availability of all active agents, resulting in a much more effective product.
That’s why Banjo is provided as a lozenge that is held in your mouth until dissolved. Active ingredients coat the mucous membrane lining your mouth, and are absorbed through that mucous membrane while the lozenge dissolves.
If you prefer, the Banjo lozenge can instead be dissolved in water to make a great tasting ‘tea.’ By slowly sipping the tea you achieve the same effect, as the tea coats the membranes of your mouth, allowing active ingredients to be absorbed.
This method of administration bypasses the harsh environment of the stomach and avoids immediate destruction of active ingredients by the liver.
Active ingredients are very rapidly absorbed – directly into the bloodstream. That’s one reason why Banjo acts so quickly. Significant relief from pain and inflammation often results within minutes.