Endotoxin shock represents an extreme in whole body inflammation. The ability of the citrus flavonoid hesperidin to suppress endotoxin induced shock suggests that it is a powerful anti-inflammatory agent.
Endotoxin shock represents an extreme in whole body inflammation. The ability of the citrus flavonoid hesperidin to suppress endotoxin induced shock suggests that it is a powerful anti-inflammatory agent.
Ginger effectively inhibits the growth of, or kills, bacteria associated with periodontitis.
So in addition to treating pain and inflammation, Banjo may also improve the health of your gums, preserve your teeth – even freshen your breath. How nice!
NF-kB seems to play an important role in muscular dystrophy. Inhibiting NF-kB leads to improvement in the mouse model of Duchenne muscular dystrophy.
Curcumin cannot, it seems, inhibit NF-kB in the muscle of patients (or at least mice) with muscular dystrophy.
While unfortunate, it suggests (along with other research) that curcumin is only effective when acting in concert with other agents. Those ‘other agents’ may be lacking in the muscle of patients with muscular dystrophy.
Inflammation in white blood cells contributes to the cause of chronic fatigue syndrome
Summary of key findings:
* Chronic fatigue syndrome is an inflammation related disease.
* NF-kB recogniged as the Master switch controlling inflammation in chronic fatigue
* Those with chronic fatigue show higher levels of activated NF-kB
* More activated NF-kB results in (correlates with) more severe disease symptoms
* Inflammation in the white blood cells plays an important role in chronic fatigue syndrome
* Chronic fatigue syndrome should be treated with agents that reduce NF-kB activation, such as anti-oxidants like turmeric (curcumin)
Curcumin, or turmeric, is believed to have many beneficial effects relative to inflammation and disease. It is an inhibitor of NF-kB, but also affects other pathways and mediators of inflammation.
Efficacy of curcumin demonstrated in rheumatoid arthritis, inflammatory eye diseases, inflammatory bowel disease, chronic pancreatitis, psoriasis, hyperlipidemia, and cancers. Patients taking up to 8 grams of pure curcumin daily for 4 months reported no significant side effects.
Curcumin is a polyphenolic compound isolated from the rhizome of the plant Curcuma longa (turmeric) that has traditionally been used for pain and wound-healing. Recent studies have shown that curcumin ameliorates (improves, helps with) multiple sclerosis, rheumatoid arthritis, psoriasis, and inflammatory bowel disease in human or animal models.
In this study, mirtazapine (an anti-depressant) is found to inhibit NF-kB activation in the brain, thereby reducing inflammation and the mediators of inflammation in the brain.
At first it’s hard to believe that any one thing could effectively treat so many ailments. But since NF-kB inhibitors fight inflammation, it makes sense. If inflammation contributes to the cause of many conditions (and it does) then whatever relieves inflammation (actually treating the cause, not just masking the symptoms) should be effective in treating many ailments.
Aging Alzheimer's Arthritis Asthma Atherosclerosis Back Pain Banjo Cancer Chronic Pain Cluster Headache Crohn's Diabetes Fatigue Fibromyalgia Gout Headache Heart Disease IBD Inflammation Joint Pain Lupus Migraine Multiple Sclerosis Muscular Dystrophy Neck Pain Neuropathic Pain NF-kB Osteoarthritis Pain Parkinson's Psoriasis Rheumatoid Arthritis Sjogren's Stroke TMJ Ulcerative Colitis
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