Ankylosing Spondylitis

Men are 3x more likely than women to develop ankylosing spondylitis (AS)

The CDC estimates that 0.6 million and 2.4 million Americans suffer with AS.

AS may be significantly underdiagnosed, especially in women, who tend to have milder symptoms.

95% of Caucasians with AS are positive for the genetic marker HLA-B27.

40% of AS cases are associated with inflammation of the eye.

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Related pages:
Autoimmune Conditions
Joint Pain
Inflammation

Ankylosing spondylitis is an autoimmune disease characterized by chronic inflammation of the spine and lower back, but which may also cause inflammation elsewhere.

Introduction to Banjo

Banjo provides fast, effective relief from pain and inflammation because it enables your body’s immune system to function properly. It works just like the fruits and vegetables you eat every day – by naturally inhibiting NF-kB, the inflammation Master Switch.

Banjo works better because it combines the most effective natural extracts and delivers them in a form that ensures maximum bio-availability. You get the full spectrum of phytonutrients your body needs to turn off excess inflammation.

Thoughts on Ankylosing Spondylitis

According to the theory advanced on this site (in brief) every ‘disease of inflammation’:

  1. Is caused by inflammation;
  2. That results from over-activation of NF-kB;
  3. Which can be treated by administering NF-kB inhibitors – especially natural (plant derived) NF-kB inhibitors.

The following – if true – would support (but not ‘prove’) the theory in regard to ankylosing spondylitis (AS):

  • AS is associated with inflammation.
  • AS is associated with excess NF-kB activation.
  • There is evidence that AS is associated with a defect (especially genetic) or vulnerability that results in excess activation of NF-kB.
  • There is evidence that inhibiting NF-kB is beneficial in the treatment of AS.
  • There is evidence that natural NF-kB inhibitors are beneficial in treating or preventing AS.
  • There is an explanation for the cause and progression of AS that is consistent with the theory.

Ankylosing spondylitis does not initially appear as though it complies well with the theory.

Nonetheless, over the course of time, especially as more research articles are accumulated, this section will be updated.

There is value in applying the template and making the strongest possible argument in favor of its validity. Should that argument be found deficient – at least we’ve learned something.

Most Recent Ankylosing Spondylitis Posts

Turmeric as wonder drug

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November 16, 2009

Turmeric as wonder drug

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Curcumin is the active ingredient of turmeric that has been consumed as a dietary spice for ages.

Curcumin, or turmeric, is believed to have many beneficial effects relative to inflammation and disease. It is an inhibitor of NF-kB, but also affects other pathways and mediators of inflammation.

The publication:

Adv Exp Med Biol. 2007;595:127-48.

Modulation of transcription factors by curcumin.

Shishodia S, Singh T, Chaturvedi MM.

Summary of the abstract

Curcumin is the active ingredient of turmeric that has been consumed as a dietary spice for ages.

Turmeric is widely used in traditional Indian medicine to cure biliary disorders, anorexia, cough, diabetic wounds, hepatic disorders, rheumatism, and sinusitis.

Extensive investigation over the last five decades has indicated that curcumin:

  • reduces blood cholesterol
  • prevents low-density lipoprotein oxidation
  • inhibits platelet aggregation
  • suppresses thrombosis and myocardial infarction

And that it suppresses symptoms associated with:

And that it:

  • inhibits HIV replication
  • enhances wound healing
  • protects from liver injury
  • increases bile secretion
  • protects from cataract formation
  • protects from pulmonary toxicity and fibrosis.

Comments:

You’re taking a daily dose of curcumin, right?

The only ‘problem’ with curcumin seems to be its low level of bio-availability. That is, not enough curcumin gets into the blood, and to the cells where it can exert its  beneficial effects.

Banjo delivers turmeric (and curcumin, its major active ingredient) trans-mucosaly. That is, the active ingredients are absorbed through the mucous membranes of the mouth. This is believed to substantially increase the bio-availability of all active agents, resulting in a much more effective product.

That’s why Banjo is provided as a lozenge that is held in your mouth until dissolved. Active ingredients coat the mucous membrane lining your mouth, and are absorbed through that mucous membrane while the lozenge dissolves.

If you prefer, the Banjo lozenge can instead be dissolved in water to make a great tasting ‘tea.’ By slowly sipping the tea you achieve the same effect, as the tea coats the membranes of your mouth, allowing active ingredients to be absorbed.

This method of administration bypasses the harsh environment of the stomach and avoids immediate destruction of active ingredients by the liver.

Active ingredients are very rapidly absorbed – directly into the bloodstream. That’s one reason why banjo acts so quickly. Significant relief from pain and inflammation often results within minutes.

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